California Medical Laboratories for Sale | Prime Business Listings
Buy a medical laboratory in California – explore exclusive listings of turnkey medical labs for sale across the Golden State. Whether you’re targeting a clinical diagnostics facility in Los Angeles, a biotech research center in the Bay Area, or a specialty testing lab in San Diego, our curated marketplace showcases modern equipment, established client bases, and transparent financials. Ideal for investors and entrepreneurs aiming to enter California’s booming healthcare sector, these acquisition opportunities deliver strong ROI and long-term growth potential. Browse now to find your perfect medical lab investment in California.
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All Matching Deals
California CLIA Laboratory License
We have a California Clinical laboratory license CLIA Waiver for Sale , CDPH, Location and Director included.
$1.5M LA Laboratory, Long Established, Contracts
Well-established California clinical laboratory with 27 years of operating history, fully equipped for clinical and molecular testing and holding highly desirable insurance contracts and credentials. - Asking Price: $500,000 - 27 years established - Active Medicare and Medi-Cal - Contracted with...
SoCal Equipped Laboratory with Medicare
Clinical laboratory, fully equipped for clinical and molecular testing, with active Medicare. Two years established, serving cash and Medicare patients. Laboratory is located in Southern California, in the property of 1,800 Sq.Ft. Lease is $4,000/month. Equipment worth about $150,000 is in...
NorCal Laboratory with Medicare, Medi-Cal, and Op
For sale active Clinical laboratory, fully equipped for clinical and molecular testing, with active Medicare and Medi-Cal. Five years established, serving Medicare and Medi-Cal patients. Laboratory is in Northern California, Lease is $5,000/month. Medical Director, Full-time CLS and Laboratory...
CLIA License High or Moderate Complexities
For sale is a California Laboratory CLIA license as an asset sale to lab professionals who need an activated CLIA license immediately. It comes with a state laboratory license and a medical director in good standing. There is no equipment or location to keep (unless negotiated extra). Asking for...
Lab with Big Customer List, PCR, Genetic, Equipped
High complexity CLIA with certificate of Compliance, in good standing, with Medical Director, Equipment, and big customers database. Medicare is active, however offered for transfer only. Lab is not serving accounts currently, due move out of state (as a pure software company) – however very active...
20M Growing Lab, Full Service, All In-Network
Broker is presenting a big, old, real full menu laboratory: all tests, all specialties, contracted with major insurances. Adding accounts and growing business daily. Tests nicely spread across all specialties, great reimbursements, where it counts. This is opportunity for investors with rolling...
30 yrs. lab, BC, BS, UHC, Health Net, Medi-Medi
Long-established laboratory with grandfathered in-network insurance contracts — including with major providers no longer extending such agreements to privately held labs. Location: Busy Medical Building in Los Angeles Valley | Gross Revenue: $1.2M/year | Net Profit: $300K/year Private PPO Contracts...
$20M+ Large Clinical Laboratory – Full Robotic
Broker is pleased to present a major clinical laboratory opportunity. Established in 2019, this laboratory operates as a fully automated, 24/7 facility with comprehensive insurance contracts and advanced infrastructure. • Robotic Automation: State-of-the-art equipment valued at over $25M, fully paid...
Laboratory with Medicare, 550K gross
Established clinical laboratory in Southern California, fully equipped for chemistry testing and operating for 2 years with an active Medicare contract. • Financials: Grossing ~$550,000 annually | Adjusted net available upon request • Facility: 1,400 SF | Lease $2,500/month (utilities included) |...
In-Network Lab: Medicare, Medi-Cal, PPOs, Medicaid
Fully licensed high-complexity CLIA-certified clinical laboratory with CAP accreditation, Medicare, and Medi-Cal provider status. This turnkey operation offers a rare opportunity for immediate activation or relocation to the buyer’s preferred site. Price: $2,500,000. Established: 2025 Certifications:...
Clinical Laboratory, netting 1M/month
Broker is pleased to offer an extraordinary opportunity to all major investors in the laboratory industry. Seller owns and operates laboratories in California, and multiple other states are offering opportunities for sale, partnership, investment, mergers, or acquisitions (partial purchasing is also...
333K Net Absentee-Owner DME Business in California
Established 28 years, this fully licensed and accredited Durable Medical Equipment (DME) provider has built a long-standing reputation serving patients across California. The company supplies equipment designed to improve mobility, comfort, and quality of life, and has also developed proprietary, patented...
In-Network Full-Service Clinical Laboratory, NORCA
In-network full-service clinical laboratory located in Northern California, operating in a strong agricultural and medical services region with limited local competition. The laboratory generates approximately $5.0M in annual gross revenue with approximately $1.0M in net income and has been established...
California Laboratory, 13 Years Medicare, Medi-Cal
Established California S-Corporation clinical laboratory with thirteen (13) years of continuous Medicare and Medi-Cal enrollment history. The laboratory has been maintained primarily for scientific research purposes and has little to no prior billing activity, preserving a clean compliance record. Key...
$6M Los Angeles County Clinical Laboratory
High-complexity clinical laboratory with California state license located in Los Angeles County. Established in 2010, this is a stable, operating laboratory with consistent monthly revenue and an experienced team in place. Ownership: LLC (50/50 ownership) Employees: 64 total (43 full-time, 21...
California State Laboratory License & CLIA Waiver
Ready-to-Transfer California Laboratory Credentials Unique opportunity to acquire an existing California State Laboratory License together with a CLIA Waiver, providing a fast-track solution for entrepreneurs, healthcare providers, and laboratory operators seeking to establish testing services in California. Included • California...
Full-Service Laboratory, Great Employees, Accounts
Business Investment is pleased to present opportunity to acquire a profitable, full-service high-complexity clinical laboratory located on the border of Los Angeles and Orange Counties. This laboratory offers a stable customer base, transferable provider contracts, and a growing profit trend. • Established:...
South OC Lab with Medicare, Medi-Cal, Accounts!
Overview Laboratory represents a rare opportunity to acquire a licensed, accredited, operational molecular diagnostics platform at a valuation significantly below replacement cost. The laboratory offers established institutional relationships, recurring revenue, scalable infrastructure, and meaningful...
Los Angeles Laboratory with Medicare and Medi-Cal
Equipped clinical laboratory licensed for both clinical and molecular testing, with active Medicare and Medi-Cal provider enrollment. Established 2019. This is a clean, established laboratory with several years of operating history: currently not active accounts, but all licenses in good status. Equipment...
SoCal Lab, Medi-Medi, Staff, Equipment, Write-Off
Big, spectacular clinical laboratory, fully equipped for infectious diseases testing, chemistry, and toxicology, with active Medicare and Medi-Cal. Seller is motivated to any deal and note. Business can be purchased with very little down plus there is nearly 2M write off opportunity on corporate...
San Diego Clinical Lab, 2.4M Gross, 1M Net
Broker is pleased to present the opportunity to acquire a profitable, full-service high-complexity clinical laboratory located in San Diego, California. • Established: 2019 • Specialties: Pharmacogenomics (PGx), Molecular Diagnostics with MolDx Z Code (Mental Health, Pain Management, Cardiovascular),...
California CDPH and CLIA Lab For Sale
We have a hike complexity, Clinical Laboratory for sale in Southern California. It has well over $100,000 worth of equipment and a clean license. It won’t last long
California Lab CDPH and CLIA Waiver
California CDPH lab licence for sake with CLIA Waiver, with location, director
California Lab with Medicare and Medi-Cal
California CDPH, CLIA, Medicare, Medi-Cal, Medicaid lab coming up for sale. Fully set up and ready for your business. No clawbacks or violations.
Tips for Buying Medical Laboratories In California
Understand Regulatory Compliance
Buying a medical laboratory in California requires a thorough understanding of state and federal regulations. The laboratory must comply with the Clinical Laboratory Improvement Amendments (CLIA), California Department of Public Health (CDPH) licensing requirements, and potentially CAP accreditation if it serves certain markets. Buyers should conduct detailed due diligence to verify that all licenses, certifications, and permits are current and in good standing. Non-compliance can lead to hefty fines, operational delays, or even license suspension, so regulatory history and compliance records should be a top priority during the evaluation process.
Assess Operational Performance and Profitability
Take a close look at the laboratory’s financial statements and key performance indicators. Scrutinize revenue streams, billing practices, payer contracts (including insurance reimbursement rates), and patient volume trends. Check if the laboratory is diversified in its client base and test offerings, which reduces dependence on just a few clients or referral sources. Potential buyers should also analyze the lab’s operational efficiencies, technology infrastructure, and staffing model—these factors can significantly impact profitability, especially in California’s competitive lab services market.
Evaluate Reputation and Growth Potential
Reputation is critical in healthcare. Review online feedback, client testimonials, and any history of complaints or litigation. Relationships with referring physicians, hospitals, and other health providers are also key assets that drive ongoing revenue. Investigate the laboratory's standing in the community, then look for untapped market opportunities—such as expanding test menus, geographical reach, or new payer relationships. A laboratory with a strong reputation and obvious pathways for growth will provide the best long-term investment potential in the dynamic California medical market.