Businesses for Sale in Pickens County, SC – Prime Local Opportunities
Discover the best Pickens County, South Carolina businesses for sale on DealStream—your one-stop marketplace for profitable SC business opportunities. Whether you’re eyeing a turnkey restaurant in Clemson, a well-established retail shop in Easley, or a service franchise near Liberty, our up-to-date Pickens County listings make buying a business easy. Browse, compare prices, and connect directly with motivated sellers today to secure your next entrepreneurial venture in Pickens County, SC.
All Matching Deals

Easley, South Carolina, Practice for Sale
Well established 'cash' practice collecting $86,721.00. Net cash flow [after add backs] $55,545.00. 100 new patients / 1,947 total visits. This is the quintessential low overhead - low stress - enjoyable practice! Open 5 'half' days only. Plenty of down time for recreation/relaxation. Plethora of outdoor...

Great Fitness Studio
This fitness gym is more than a cycling studio—it’s a vibrant community dedicated to transforming fitness journeys. They blend high-energy spin classes with immersive music, dynamic lighting, and top-tier coaching to create a workout experience that’s both exhilarating and empowering. This studio...

Construction Business for Sale in Pickens County
LISTING ID # 33418 Specializing in the installation of all types of siding and services for the exterior of residential dwellings and structures. Replacement windows, Decks, Metal Awnings, Screened Enclosures, Detached Garages, Storage Sheds. The current owner only advertises by the company website....
Tips for Buying A Business In Pickens County, SC
Do Your Local Market Research
Before making any offers, take the time to thoroughly understand the Pickens County market. Investigate local trends, demographics, and the competitive landscape for your desired industry. Visit potential neighborhoods, chat with other business owners, and consult with local business associations. This groundwork will help you identify opportunities and potential threats, ensuring you invest in a business model that’s suited for the unique qualities of the Pickens County area.
Assess Business Financials and Operations
Carefully review the financials of any business you're considering. Request at least three years of profit and loss statements, tax returns, and balance sheets. Don’t just look at the numbers—ask questions about seasonality, staff turnover, and unique operational challenges specific to the region. Consider hiring a local accountant familiar with South Carolina regulations to assist in your due diligence, and identify any red flags before you commit.
Build Relationships with Key Stakeholders
Establishing positive relationships with important stakeholders—including employees, customers, and suppliers—can make or break your post-purchase transition. Set up introductory meetings with long-standing staff, and introduce yourself to suppliers and regular customers if possible. Let people know your intentions to continue the legacy or improve the business. In a close-knit region like Pickens County, a good reputation and strong relationships can give you a significant advantage and smooth the path to success.
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Independent Propane Distribution Sales and Service
Well established family owned, independent propane distribution, heater sales/installation and service business that caters to residential, commercial and agricultural accounts. With over 650 plus current accounts (most of which are gas), the business continues to grow servicing 4 central South Carolina...

Highly Profitable and Advanced Security Design
This well-established company, operating for decades in the coastal South Carolina area, specializes in the design and installation of security and video surveillance systems for commercial institutions. The business has cultivated a strong network and reputation with its established clients. Its commitment...

Leading Forestry and Fleet Services in the Southeast with $15MM in Revenue
This well-established 19-year old business has earned a stellar reputation for delivering comprehensive services in the forestry and heavy truck maintenance industries. Operating out of South Carolina, the business provides a full spectrum of services, including timber procurement, harvesting, hauling,...

AV/IT Business – Turnkey & Scalable SC/NC/GA
This successful technology solutions firm is a leader in delivering innovative services tailored to the unique needs of various sectors, including public and private organizations. Key Services Offered: -Data Management Solutions: Streamlined data systems designed to improve organizational productivity. -Voice...

Reduced Price: Construction Equipment Sales - Regional presence in SC
Growth opportunity: Approved as a dealer with the following OEM: Yanmar, AUSA, Kioti in both SC for new equipment as well. This well-established Charleston, SC equipment dealership presents a unique opportunity for buyers seeking to enter the lucrative machinery market. Specializing in both new...

Electrical Contractor Serving the Southeast 46 Years of Excellence
Acquisition Opportunity: Electrical Contractor Serving the Southeast 46 Years of Excellence in Commercial & Institutional Projects Electrical Contractor Serving the Southeast This well-established electrical contracting business has built an excellent reputation over the past four decades for...

Real Estate Sign Installation Business
The company provides post installation and removal for residential real estate signs throughout the Central Midlands region of South Carolina. The business serves over 100 real estate companies and 300+ agents, offering online ordering, responsive customer support, and efficient field service through...

Own a Premier Staffing Franchise in Rock Hill, SC
For discerning investors seeking a turn-key business venture with proven profitability, this Express Employment Professionals staffing franchise in Rock Hill, South Carolina, presents an unparalleled opportunity. Priced at $1,034,900, this established business combines a legacy of success with immense...
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